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EMD-26989
Extracellular architecture of an engineered canonical Wnt signaling ternary complex
EMD-26989
Single-particle3.8 Å
Deposition: 14/05/2022Map released: 15/03/2023
Last modified: 13/11/2024
Sample Organism:
Mus musculus,
Xenopus laevis,
Homo sapiens
Sample: haXWnt8-mFzd8CRD-hLRP6E1E2
Fitted models: 8ctg
Deposition Authors: Tsutsumi N
,
Jude KM ,
Garcia KC
Sample: haXWnt8-mFzd8CRD-hLRP6E1E2
Fitted models: 8ctg
Deposition Authors: Tsutsumi N
,
Jude KM ,
Garcia KC
Structure of the Wnt-Frizzled-LRP6 initiation complex reveals the basis for coreceptor discrimination.
Tsutsumi N ,
Hwang S,
Waghray D,
Hansen S,
Jude KM ,
Wang N ,
Miao Y ,
Glassman CR,
Caveney NA ,
Janda CY,
Hannoush RN ,
Garcia KC
(2023) PNAS , 120 , e2218238120 - e2218238120
,
Hwang S,
Waghray D,
Hansen S,
Jude KM ,
Wang N ,
Miao Y ,
Glassman CR,
Caveney NA ,
Janda CY,
Hannoush RN ,
Garcia KC
(2023) PNAS , 120 , e2218238120 - e2218238120
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R37AI051321 (United States)
- Howard Hughes Medical Institute (HHMI): (United States)
- Ludwig Institute for Cancer Research (LICR): (United States)