EMD-26486

Single-particle
2.58 Å
EMD-26486
3D View Gallery
Deposition: 24/03/2022
Map released: 18/05/2022
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26486

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7ug7 summary report (pdf.gz) Map-7ug7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B

EMD-26486

Single-particle
2.58 Å
EMD-26486
3D View Gallery
Deposition: 24/03/2022
Map released: 18/05/2022
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli, Escherichia coli K-12, Actinoplanes sp.
Sample: 70S ribosome in an intermediate state of translocation bound to EF-G(GDP) and ArgyrinB
Fitted models: 7ug7

Deposition Authors: Rundlet EJ , Wieland M , Holm M, Koller TO , Blanchard SC , Wilson DN
The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Wieland M , Holm M, Rundlet EJ , Morici M , Koller TO , Maviza TP , Pogorevc D, Osterman IA , Muller R , Blanchard SC , Wilson DN
(2022) PNAS , 119 , e2114214119 - e2114214119
PUBMED: 35500116
DOI: doi:10.1073/pnas.2114214119
ISSN: 1091-6490
ASTM: PNASA6