EMD-26423

Single-particle
2.4 Å
EMD-26423
3D View Gallery
Deposition: 12/03/2022
Map released: 02/11/2022
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26423
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7uaf summary report (pdf.gz) Map and 7uaf FULL report (pdf.gz)
EMICSS annotations (xml)

Human meprin alpha inhibitory complex with compound 10d (N~3~,N~3~-bis[(2H-1,3-benzodioxol-5-yl)methyl]-N-hydroxy-beta-alaninamide)

EMD-26423

Single-particle
2.4 Å
EMD-26423
3D View Gallery
Deposition: 12/03/2022
Map released: 02/11/2022
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Tetrameric portion of helical meprin alpha in complex with a small molecule inhibitor
Fitted models: 7uaf

Deposition Authors: Bayly-Jones C , Lupton CJ , Fritz C , Schlenzig D , Whisstock JC
Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Bayly-Jones C , Lupton CJ , Fritz C , Venugopal H , Ramsbeck D , Wermann M, Jager C , de Marco A , Schilling S, Schlenzig D , Whisstock JC
(2022) Nat Commun , 13 , 6178 - 6178
PUBMED: 36261433
DOI: doi:10.1038/s41467-022-33893-7
ISSN: 2041-1723