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EMD-26423
Human meprin alpha inhibitory complex with compound 10d (N~3~,N~3~-bis[(2H-1,3-benzodioxol-5-yl)methyl]-N-hydroxy-beta-alaninamide)
EMD-26423
Single-particle2.4 Å
Deposition: 12/03/2022Map released: 02/11/2022
Last modified: 16/10/2024
Sample Organism:
Homo sapiens
Sample: Tetrameric portion of helical meprin alpha in complex with a small molecule inhibitor
Fitted models: 7uaf
Deposition Authors: Bayly-Jones C
,
Lupton CJ ,
Fritz C ,
Schlenzig D ,
Whisstock JC
Sample: Tetrameric portion of helical meprin alpha in complex with a small molecule inhibitor
Fitted models: 7uaf
Deposition Authors: Bayly-Jones C
,
Lupton CJ ,
Fritz C ,
Schlenzig D ,
Whisstock JC
Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Bayly-Jones C ,
Lupton CJ ,
Fritz C ,
Venugopal H ,
Ramsbeck D ,
Wermann M,
Jager C ,
de Marco A ,
Schilling S,
Schlenzig D ,
Whisstock JC
(2022) Nat Commun , 13 , 6178 - 6178
,
Lupton CJ ,
Fritz C ,
Venugopal H ,
Ramsbeck D ,
Wermann M,
Jager C ,
de Marco A ,
Schilling S,
Schlenzig D ,
Whisstock JC
(2022) Nat Commun , 13 , 6178 - 6178
Grant Support:
- German Federal Ministry for Education and Research: (Germany)
- Australian Research Council (ARC): (Australia)