Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-26422
Human meprin alpha (active state)[subparticle localised reconstruction]
EMD-26422
Single-particle2.6 Å
Deposition: 12/03/2022Map released: 02/11/2022
Last modified: 30/10/2024
Sample Organism:
Homo sapeins,
Homo sapiens
Sample: Single subunit of helical meprin alpha in the active state
Fitted models: 7uae
Deposition Authors: Bayly-Jones C
,
Lupton CJ ,
Fritz C ,
Schlenzig D ,
Whisstock JC
Sample: Single subunit of helical meprin alpha in the active state
Fitted models: 7uae
Deposition Authors: Bayly-Jones C
,
Lupton CJ ,
Fritz C ,
Schlenzig D ,
Whisstock JC
Helical ultrastructure of the metalloprotease meprin alpha in complex with a small molecule inhibitor.
Bayly-Jones C ,
Lupton CJ ,
Fritz C ,
Venugopal H ,
Ramsbeck D ,
Wermann M,
Jager C ,
de Marco A ,
Schilling S,
Schlenzig D ,
Whisstock JC
(2022) Nat Commun , 13 , 6178 - 6178
,
Lupton CJ ,
Fritz C ,
Venugopal H ,
Ramsbeck D ,
Wermann M,
Jager C ,
de Marco A ,
Schilling S,
Schlenzig D ,
Whisstock JC
(2022) Nat Commun , 13 , 6178 - 6178
Grant Support:
- German Federal Ministry for Education and Research: (Germany)
- Australian Research Council (ARC): (Australia)