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EMD-26322
MVV cleaved synaptic complex (CSC) intasome at 3.4 A resolution
EMD-26322
Single-particle3.46 Å
Deposition: 25/02/2022Map released: 11/05/2022
Last modified: 28/05/2025
Sample Organism:
synthetic construct,
Streptomyces griseus,
Visna/maedi virus EV1 KV1772
Sample: MVV cleaved synaptic complex intasome
Fitted models: 7u32
Deposition Authors: Shan Z
,
Pye VE ,
Cherepanov P ,
Lyumkis D
Sample: MVV cleaved synaptic complex intasome
Fitted models: 7u32
Deposition Authors: Shan Z
,
Pye VE ,
Cherepanov P ,
Lyumkis D
Multivalent interactions essential for lentiviral integrase function.
Ballandras-Colas A ,
Chivukula V ,
Gruszka DT ,
Shan Z ,
Singh PK ,
Pye VE ,
McLean RK ,
Bedwell GJ,
Li W,
Nans A ,
Cook NJ ,
Fadel HJ,
Poeschla EM ,
Griffiths DJ ,
Vargas J,
Taylor IA ,
Lyumkis D ,
Yardimci H ,
Engelman AN ,
Cherepanov P
(2022) Nat Commun , 13 , 2416 - 2416
,
Chivukula V ,
Gruszka DT ,
Shan Z ,
Singh PK ,
Pye VE ,
McLean RK ,
Bedwell GJ,
Li W,
Nans A ,
Cook NJ ,
Fadel HJ,
Poeschla EM ,
Griffiths DJ ,
Vargas J,
Taylor IA ,
Lyumkis D ,
Yardimci H ,
Engelman AN ,
Cherepanov P
(2022) Nat Commun , 13 , 2416 - 2416
Grant Support:
- National Science Foundation (NSF, United States): MCB-2048095 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): U54 AI150472 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01 AI136680 (United States)
- The Francis Crick Institute: FC10061 (United Kingdom)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): P50AI150481 (United States)