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EMD-26306

Single-particle
4.6 Å
EMD-26306
3D View Gallery
Deposition: 22/02/2022
Map released: 16/11/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26306
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7u23 summary report (pdf.gz) Map and 7u23 FULL report (pdf.gz)
EMICSS annotations (xml)

Single-chain LCDV-1 viral insulin-like peptide bound to IGF-1R ectodomain, leucine-zippered form

EMD-26306

Single-particle
4.6 Å
EMD-26306
3D View Gallery
Deposition: 22/02/2022
Map released: 16/11/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lymphocystis disease virus 1
Sample: 2:1 complex of scLCDV-1 and IGF-1Rzip
Fitted models: 7u23

Deposition Authors: Kirk NS , Lawrence MC
Interaction of a viral insulin-like peptide with the IGF-1 receptor produces a natural antagonist.
Moreau F , Kirk NS , Zhang F, Gelfanov V, List EO, Chrudinova M , Venugopal H , Lawrence MC , Jimenez V , Bosch F , Kopchick JJ , DiMarchi RD , Altindis E , Ronald Kahn C
(2022) Nat Commun , 13 , 6700 - 6700
PUBMED: 36335114
DOI: doi:10.1038/s41467-022-34391-6
ISSN: 2041-1723