EMD-26276

Helical reconstruction
2.9 Å
EMD-26276
3D View Gallery
Deposition: 19/02/2022
Map released: 23/03/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26276
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7u13 summary report (pdf.gz) Map and 7u13 FULL report (pdf.gz)
EMICSS annotations (xml)

TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4).

EMD-26276

Helical reconstruction
2.9 Å
EMD-26276
3D View Gallery
Deposition: 19/02/2022
Map released: 23/03/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TMEM106B(120-254) singlet amyloid fibril from dementia with Lewy bodies (DLB)
Fitted models: 7u13

Deposition Authors: Fitzpatrick AWP , Stowell MHB
Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Chang A , Xiang X , Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J , Heeman B , Forgrave LM, DeTure M, DeMarco ML , Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB , Mackenzie IRA, Fitzpatrick AWP
(2022) Cell , 185 , 1346 - 1355.e15
PUBMED: 35247328
DOI: doi:10.1016/j.cell.2022.02.026
ISSN: 1097-4172