EMD-26201
Cryo-EM structure of SARS-CoV-2 spike in complex with FSR22, an anti-SARS-CoV-2 DARPin (Local refinement of FSR22 and RBD)
EMD-26201
Single-particle4.17 Å
Deposition: 15/02/2022Map released: 07/12/2022
Last modified: 09/10/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Escherichia phage EcSzw-2Escherichia coli
Sample: DARPin FSR22 in complex with RBD of SARS-CoV-2 spike
Fitted models: 7tz0
Deposition Authors: Kwon YD
,
Gorman J
Sample: DARPin FSR22 in complex with RBD of SARS-CoV-2 spike
Fitted models: 7tz0
Deposition Authors: Kwon YD
,
Gorman J
A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins.
Chonira V ,
Kwon YD ,
Gorman J ,
Case JB ,
Ku Z,
Simeon R,
Casner RG,
Harris DR ,
Olia AS,
Stephens T,
Shapiro L,
Bender MF ,
Boyd H ,
Teng IT,
Tsybovsky Y ,
Krammer F,
Zhang N,
Diamond MS ,
Kwong PD ,
An Z ,
Chen Z
(2023) Nat Chem Biol , 19 , 284 - 291
,
Kwon YD ,
Gorman J ,
Case JB ,
Ku Z,
Simeon R,
Casner RG,
Harris DR ,
Olia AS,
Stephens T,
Shapiro L,
Bender MF ,
Boyd H ,
Teng IT,
Tsybovsky Y ,
Krammer F,
Zhang N,
Diamond MS ,
Kwong PD ,
An Z ,
Chen Z
(2023) Nat Chem Biol , 19 , 284 - 291
Grant Support: