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EMD-26185

Single-particle
3.4 Å
EMD-26185
3D View Gallery
Deposition: 13/02/2022
Map released: 15/02/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26185
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7tym summary report (pdf.gz) Map and 7tym FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM Structure of insulin receptor-related receptor (IRR) in active-state captured at pH 9. The 3D refinement was applied with C2 symmetry

EMD-26185

Single-particle
3.4 Å
EMD-26185
3D View Gallery
Deposition: 13/02/2022
Map released: 15/02/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Insulin receptor-related receptor (IRR) in active-state captured at pH 9
Fitted models: 7tym

Deposition Authors: Wang LW, Hall C , Li J , Choi E , Bai XC
Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor.
Wang L , Hall C , Li J , Choi E , Bai XC
(2023) Nat Struct Mol Biol , 30 , 661 - 669
PUBMED: 37055497
DOI: doi:10.1038/s41594-023-00974-0
ISSN: 1545-9985