EMD-26160

Single-particle
3.0 Å
EMD-26160
3D View Gallery
Deposition: 09/02/2022
Map released: 15/03/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26160

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7txt summary report (pdf.gz) Map-7txt FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of human serotonin transporter bound to small molecule '8090 in lipid nanodisc and NaCl

EMD-26160

Single-particle
3.0 Å
EMD-26160
3D View Gallery
Deposition: 09/02/2022
Map released: 15/03/2023
Last modified: 06/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Human serotonin transporter in complex with Fab15B8 bound to '8090 in NaCl
Fitted models: 7txt

Deposition Authors: Singh I, Seth A
Structure-based discovery of conformationally selective inhibitors of the serotonin transporter.
Singh I, Seth A, Billesbolle CB, Braz J, Rodriguiz RM, Roy K, Bekele B, Craik V , Huang XP, Boytsov D, Pogorelov VM, Lak P, O'Donnell H, Sandtner W, Irwin JJ, Roth BL, Basbaum AI, Wetsel WC, Manglik A, Shoichet BK, Rudnick G
(2023) Cell , 186 , 2160 - 2175.e17
PUBMED: 37137306
DOI: doi:10.1016/j.cell.2023.04.010
ISSN: 1097-4172