EMD-26098

Single-particle
2.8 Å
EMD-26098
3D View Gallery
Deposition: 29/01/2022
Map released: 27/04/2022
Last modified: 21/02/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26098

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7trj summary report (pdf.gz) Map-7trj FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

The eukaryotic translation initiation factor 2B from Homo sapiens with a H160D mutation in the beta subunit

EMD-26098

Single-particle
2.8 Å
EMD-26098
3D View Gallery
Deposition: 29/01/2022
Map released: 27/04/2022
Last modified: 21/02/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Translation initiation factor eIF-2B decamer
Fitted models: 7trj

Deposition Authors: Wang L , Schoof M , Lawrence R, Boone M , Frost A , Walter P
A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation.
Boone M , Wang L , Lawrence R, Frost A , Walter P , Schoof M
(2022) eLife , 11
PUBMED: 35416150
DOI: doi:10.7554/eLife.76171
ISSN: 2050-084X
Grant Support: