EMD-26037
E. coli 70S ribosomes bound with the ALS/FTD-associated dipeptide repeat protein PR20
EMD-26037
Single-particle2.9 Å
Deposition: 24/01/2022Map released: 25/05/2022
Last modified: 21/02/2024
Sample Organism:
Escherichia coli,
Homo sapiens
Sample: E. coli 70S ribosome bound with the ALS/FTD-associated dipeptide repeat protein PR20
Fitted models: 7tos
Deposition Authors: Loveland AB
,
Svidritskiy E,
Susorov D ,
Lee S,
Park A,
Zvornicanin S,
Demo G ,
Gao FB ,
Korostelev AA
Sample: E. coli 70S ribosome bound with the ALS/FTD-associated dipeptide repeat protein PR20
Fitted models: 7tos
Deposition Authors: Loveland AB
,
Svidritskiy E,
Susorov D ,
Lee S,
Park A,
Zvornicanin S,
Demo G ,
Gao FB ,
Korostelev AA
Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Loveland AB ,
Svidritskiy E,
Susorov D ,
Lee S,
Park A,
Zvornicanin S,
Demo G ,
Gao FB ,
Korostelev AA
(2022) Nat Commun , 13 , 2776 - 2776
,
Svidritskiy E,
Susorov D ,
Lee S,
Park A,
Zvornicanin S,
Demo G ,
Gao FB ,
Korostelev AA
(2022) Nat Commun , 13 , 2776 - 2776
Grant Support:
- Other private: Dan and Diane Riccio Fund for Neuroscience (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM107465 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM127094 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R01NS101986 (United States)