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EMD-26036
Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20
EMD-26036
Single-particle2.9 Å
Deposition: 24/01/2022Map released: 25/05/2022
Last modified: 13/11/2024
Sample Organism:
Oryctolagus cuniculus,
Escherichia coli K-12,
Homo sapiens,
Saccharomyces cerevisiae
Sample: Mamalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20
Fitted models: 7tor
Deposition Authors: Loveland AB
,
Svidritskiy E,
Susorov D
,
Lee S,
Park A,
Zvornicanin S,
Demo G
,
Gao FB
,
Korostelev AA
Sample: Mamalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20
Fitted models: 7tor
Deposition Authors: Loveland AB
,
Svidritskiy E,
Susorov D
,
Lee S,
Park A,
Zvornicanin S,
Demo G
,
Gao FB
,
Korostelev AA
Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Loveland AB
,
Svidritskiy E,
Susorov D
,
Lee S,
Park A,
Zvornicanin S,
Demo G
,
Gao FB
,
Korostelev AA
(2022) Nat Commun , 13 , 2776 - 2776
,
Svidritskiy E,
Susorov D
,
Lee S,
Park A,
Zvornicanin S,
Demo G
,
Gao FB
,
Korostelev AA
(2022) Nat Commun , 13 , 2776 - 2776
Grant Support:
- Other private: Dan and Diane Riccio Fund for Neuroscience
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM107465 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM127094 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R01NS101986 (United States)
