Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-26003

Single-particle
3.2 Å
EMD-26003
3D View Gallery
Deposition: 20/01/2022
Map released: 15/02/2023
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-26003
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7tmw summary report (pdf.gz) Map and 7tmw FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the relaxin receptor RXFP1 in complex with heterotrimeric Gs

EMD-26003

Single-particle
3.2 Å
EMD-26003
3D View Gallery
Deposition: 20/01/2022
Map released: 15/02/2023
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Complex of the relaxin receptor RXFP1 and heterotrimeric Gs
Fitted models: 7tmw

Deposition Authors: Erlandson SC, Rawson S
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition.
Erlandson SC, Rawson S , Osei-Owusu J , Brock KP, Liu X, Paulo JA , Mintseris J, Gygi SP , Marks DS, Cong X , Kruse AC
(2023) Nat Chem Biol , 19 , 1013 - 1021
PUBMED: 37081311
DOI: doi:10.1038/s41589-023-01321-6
ISSN: 1552-4469