Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-25926

Single-particle
2.7 Å
EMD-25926 Deposition: 16/01/2022
Map released: 05/10/2022
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25926

S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with flexible Orc6 N-terminal domain

EMD-25926

Single-particle
2.7 Å
EMD-25926 Deposition: 16/01/2022
Map released: 05/10/2022
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae
Sample: ORC in complex with ARS1 DNA and Cdc6
Fitted models: 7tji

Deposition Authors: Schmidt JM , Yang R
A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Schmidt JM , Yang R , Kumar A , Hunker O, Seebacher J , Bleichert F
(2022) Nat Commun , 13 , 1059 - 1059
PUBMED: 35217664
DOI: doi:10.1038/s41467-022-28695-w
ISSN: 2041-1723