EMD-25906

Single-particle
5.2 Å
EMD-25906
3D View Gallery
Deposition: 12/01/2022
Map released: 28/12/2022
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25906

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7thy summary report (pdf.gz) Map-7thy FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of Leucine Rich Repeat Kinase 2's ROC domain interacting with the microtubule facing the minus end

EMD-25906

Single-particle
5.2 Å
EMD-25906
3D View Gallery
Deposition: 12/01/2022
Map released: 28/12/2022
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: LRRK2RCKW filament bound to a 11-pf microtubule with MLi-2 present
Fitted models: 7thy

Deposition Authors: Matyszewski M , Leschziner AE
Structural basis for Parkinson's disease-linked LRRK2's binding to microtubules.
Snead DM, Matyszewski M , Dickey AM , Lin YX, Leschziner AE , Reck-Peterson SL
(2022) Nat Struct Mol Biol , 29 , 1196 - 1207
PUBMED: 36510024
DOI: doi:10.1038/s41594-022-00863-y
ISSN: 1545-9985