Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-25776

Single-particle
2.0 Å
EMD-25776
3D View Gallery
Deposition: 20/12/2021
Map released: 25/01/2023
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25776
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7taj summary report (pdf.gz) Map and 7taj FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of Human Enterovirus D68 US/MO/14-18947 strain in complex with inhibitor 11526093 (no/low occupancy-no inhibitor modeled)

EMD-25776

Single-particle
2.0 Å
EMD-25776
3D View Gallery
Deposition: 20/12/2021
Map released: 25/01/2023
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: enterovirus D68
Sample: enterovirus D68
Fitted models: 7taj

Deposition Authors: Fu J , Klose T

Isoxazole-3-Carboxamide Derivatives of Pleconaril Destabilize the Viral Capsid of Enterovirus-D68
Lane T, Fu J , Sherry B , Tarbet B , Hurst BL , Riabova O , Kazakova E, Egorova A , Clarke P, Leser S, Frost J, Rudy M , Tyler K, Klose T , Kuhn RJ , Makarov V, Ekins S
To Be Published