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EMD-25743

Single-particle
3.8 Å
EMD-25743
3D View Gallery
Deposition: 16/12/2021
Map released: 27/07/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25743
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7t8b summary report (pdf.gz) Map and 7t8b FULL report (pdf.gz)
EMICSS annotations (xml)

Octameric Human Twinkle Helicase Clinical Variant W315L

EMD-25743

Single-particle
3.8 Å
EMD-25743
3D View Gallery
Deposition: 16/12/2021
Map released: 27/07/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Heptameric Human Twinkle Clinical Variant W315L
Fitted models: 7t8b

Deposition Authors: Riccio AA , Bouvette J
Structural insight and characterization of human Twinkle helicase in mitochondrial disease.
Riccio AA , Bouvette J , Perera L, Longley MJ , Krahn JM , Williams JG , Dutcher R , Borgnia MJ , Copeland WC
(2022) PNAS , 119 , e2207459119 - e2207459119
PUBMED: 35914129
DOI: doi:10.1073/pnas.2207459119
ISSN: 1091-6490
ASTM: PNASA6