Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-25739

Subtomogram averaging
10.0 Å
EMD-25739
3D View Gallery
Deposition: 15/12/2021
Map released: 09/02/2022
Last modified: 28/02/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25739
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7t7v summary report (pdf.gz) Map and 7t7v FULL report (pdf.gz)
EMICSS annotations (xml)

Composite map of Lateral Munc13-1 C1-C2B-MUN-C2C molecule

EMD-25739

Subtomogram averaging
10.0 Å
EMD-25739
3D View Gallery
Deposition: 15/12/2021
Map released: 09/02/2022
Last modified: 28/02/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: 2D crystal of Munc13-1 C1-C2B-MUN-C2C domains between two lipid bilayers.
Fitted models: 7t7v

Deposition Authors: Grushin K, Sindelar CV
Munc13 structural transitions and oligomers that may choreograph successive stages in vesicle priming for neurotransmitter release.
Grushin K, Kalyana Sundaram RV , Sindelar CV , Rothman JE
(2022) PNAS , 119
PUBMED: 35135883
DOI: doi:10.1073/pnas.2121259119
ISSN: 1091-6490
ASTM: PNASA6