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EMD-25710

Single-particle
4.05 Å
EMD-25710
3D View Gallery
Deposition: 13/12/2021
Map released: 20/07/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25710
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7t65 summary report (pdf.gz) Map and 7t65 FULL report (pdf.gz)
EMICSS annotations (xml)

Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the open state

EMD-25710

Single-particle
4.05 Å
EMD-25710
3D View Gallery
Deposition: 13/12/2021
Map released: 20/07/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Oryctolagus cuniculus, Homo sapiens
Sample: Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the open state
Fitted models: 7t65

Deposition Authors: Iyer KA , Hu Y, Murayama T , Samso M
Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Iyer KA , Hu Y, Klose T , Murayama T , Samso M
(2022) PNAS , 119 , e2122140119 - e2122140119
PUBMED: 35867837
DOI: doi:10.1073/pnas.2122140119
ISSN: 1091-6490
ASTM: PNASA6