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EMD-25687
CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with NRP2 and neutralizing fabs 8I21 and 13H11
EMD-25687
Single-particle3.1 Å
Deposition: 10/12/2021Map released: 23/03/2022
Last modified: 30/10/2024
Sample Organism:
Human betaherpesvirus 5,
Homo sapiens
Sample: Pentameric complex of HCMV proteins gH, gL, UL128, UL130, UL131A bound to Neuropilin 2 and fabs of human neutralizing antibodies 8I21 and 13H11
Fitted models: 7t4s
Deposition Authors: Kschonsak M
,
Johnson MC
Sample: Pentameric complex of HCMV proteins gH, gL, UL128, UL130, UL131A bound to Neuropilin 2 and fabs of human neutralizing antibodies 8I21 and 13H11
Fitted models: 7t4s
Deposition Authors: Kschonsak M
,
Johnson MC
Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Kschonsak M ,
Johnson MC ,
Schelling R,
Green EM,
Rouge L ,
Ho H ,
Patel N ,
Kilic C,
Kraft E ,
Arthur CP ,
Rohou AL,
Comps-Agrar L ,
Martinez-Martin N,
Perez L ,
Payandeh J ,
Ciferri C
(2022) Sci Adv , 8 , eabm2536 - eabm2536
,
Johnson MC ,
Schelling R,
Green EM,
Rouge L ,
Ho H ,
Patel N ,
Kilic C,
Kraft E ,
Arthur CP ,
Rohou AL,
Comps-Agrar L ,
Martinez-Martin N,
Perez L ,
Payandeh J ,
Ciferri C
(2022) Sci Adv , 8 , eabm2536 - eabm2536
Grant Support: