EMD-25622
Negative Stain EM reconstruction of ApexGT3 in complex with two copies of PG9 Fab
EMD-25622
Single-particle26.0 Å
Deposition: 06/12/2021Map released: 19/10/2022
Last modified: 16/11/2022
Sample Organism:
Human immunodeficiency virus 1
Sample: ApexGT3 in complex with two copies of PG9 Fab
Deposition Authors: Berndsen ZT
Sample: ApexGT3 in complex with two copies of PG9 Fab
Deposition Authors: Berndsen ZT
Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors.
Willis JR,
Berndsen ZT ,
Ma KM,
Steichen JM,
Schiffner T ,
Landais E,
Liguori A,
Kalyuzhniy O,
Allen JD ,
Baboo S ,
Omorodion O ,
Diedrich JK,
Hu X,
Georgeson E,
Phelps N,
Eskandarzadeh S,
Groschel B,
Kubitz M,
Adachi Y,
Mullin TM,
Alavi NB,
Falcone S,
Himansu S ,
Carfi A,
Wilson IA,
Paulson JC,
Crispin M ,
Ward AB,
Schief WR
(2022) Immunity , 55 , 2149 - 2167.e9
,
Ma KM,
Steichen JM,
Schiffner T ,
Landais E,
Liguori A,
Kalyuzhniy O,
Allen JD ,
Baboo S ,
Omorodion O ,
Diedrich JK,
Hu X,
Georgeson E,
Phelps N,
Eskandarzadeh S,
Groschel B,
Kubitz M,
Adachi Y,
Mullin TM,
Alavi NB,
Falcone S,
Himansu S ,
Carfi A,
Wilson IA,
Paulson JC,
Crispin M ,
Ward AB,
Schief WR
(2022) Immunity , 55 , 2149 - 2167.e9
Grant Support:
- Bill & Melinda Gates Foundation: OPP1084519 (United States)
- Bill & Melinda Gates Foundation: OPP1196345 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): UM1 Al100663 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): UM1 AI144462 (United States)