EMD-25585

Single-particle
3.0 Å
EMD-25585
3D View Gallery
Deposition: 30/11/2021
Map released: 13/07/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25585

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7t0z summary report (pdf.gz) Map-7t0z FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Complex of GABA-A synaptic receptor with autoimmune antibody Fab175

EMD-25585

Single-particle
3.0 Å
EMD-25585
3D View Gallery
Deposition: 30/11/2021
Map released: 13/07/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex between autoantibody Fab175 and the a2b2g2 GABA-A receptor
Fitted models: 7t0z

Deposition Authors: Noviello CM , Hibbs RE, Kreye J , Teng J, Pruss H
Structural mechanisms of GABA A receptor autoimmune encephalitis.
Noviello CM , Kreye J , Teng J, Pruss H, Hibbs RE
(2022) Cell , 185 , 2469
PUBMED: 35803245
DOI: doi:10.1016/j.cell.2022.06.025
ISSN: 1097-4172