EMD-25559

Single-particle
3.4 Å
EMD-25559
3D View Gallery
Deposition: 25/11/2021
Map released: 22/12/2021
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25559

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7sz1 summary report (pdf.gz) Map-7sz1 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of the extracellular module of the full-length EGFR L834R bound to EGF. "tips-separated" conformation

EMD-25559

Single-particle
3.4 Å
EMD-25559
3D View Gallery
Deposition: 25/11/2021
Map released: 22/12/2021
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: full-length human EGFR(L834R):EGF complex
Fitted models: 7sz1

Deposition Authors: Huang Y , Ognjenovic J
A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Huang Y , Ognjenovic J, Karandur D , Miller K , Merk A, Subramaniam S , Kuriyan J
(2021) eLife , 10
PUBMED: 34846302
DOI: doi:10.7554/eLife.73218
ISSN: 2050-084X
Grant Support: