Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-25532
Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure 6(delta dII)
EMD-25532
Single-particle4.5 Å
Deposition: 25/11/2021Map released: 13/07/2022
Last modified: 05/06/2024
Sample Organism:
Oryctolagus cuniculus,
hepatitis C virus genotype 1a
Sample: 40S ribosomal small subunit with HCV IRES
Fitted models: 7syl
Deposition Authors: Brown ZP
,
Abaeva IS,
De S,
Hellen CUT
,
Pestova TV
,
Frank J
Sample: 40S ribosomal small subunit with HCV IRES
Fitted models: 7syl
Deposition Authors: Brown ZP
,
Abaeva IS,
De S,
Hellen CUT
,
Pestova TV
,
Frank J
Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Brown ZP
,
Abaeva IS,
De S,
Hellen CUT
,
Pestova TV
,
Frank J
(2022) EMBO J , 41 , e110581 - e110581
,
Abaeva IS,
De S,
Hellen CUT
,
Pestova TV
,
Frank J
(2022) EMBO J , 41 , e110581 - e110581
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35 GM139453 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01 GM55440 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): 1R35GM122602 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): 1R01AI123406 (United States)
