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EMD-25471
Structure of EBOV GP lacking the mucin-like domain with 1C11 scFv and 1C3 Fab bound
EMD-25471
Single-particle3.59 Å
Deposition: 19/11/2021Map released: 06/04/2022
Last modified: 28/05/2025
Sample Organism:
Homo sapiens,
Ebola virus - Gabon (1994-1997),
Zaire ebolavirus
Sample: Complex of EBOV GP lacking the mucin-like-domain with 1C11 scFv and 1C3 Fab
Fitted models: 7swd
Deposition Authors: Milligan JC, Yu X
Sample: Complex of EBOV GP lacking the mucin-like-domain with 1C11 scFv and 1C3 Fab
Fitted models: 7swd
Deposition Authors: Milligan JC, Yu X
Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses.
Milligan JC,
Davis CW ,
Yu X ,
Ilinykh PA,
Huang K,
Halfmann PJ,
Cross RW,
Borisevich V,
Agans KN ,
Geisbert JB,
Chennareddy C,
Goff AJ,
Piper AE,
Hui S ,
Shaffer KCL,
Buck T,
Heinrich ML,
Branco LM,
Crozier I,
Holbrook MR,
Kuhn JH ,
Kawaoka Y,
Glass PJ,
Bukreyev A,
Geisbert TW,
Worwa G,
Ahmed R,
Saphire EO
(2022) Cell , 185 , 995 - 1007.e18
,
Yu X ,
Ilinykh PA,
Huang K,
Halfmann PJ,
Cross RW,
Borisevich V,
Agans KN ,
Geisbert JB,
Chennareddy C,
Goff AJ,
Piper AE,
Hui S ,
Shaffer KCL,
Buck T,
Heinrich ML,
Branco LM,
Crozier I,
Holbrook MR,
Kuhn JH ,
Kawaoka Y,
Glass PJ,
Bukreyev A,
Geisbert TW,
Worwa G,
Ahmed R,
Saphire EO
(2022) Cell , 185 , 995 - 1007.e18
Grant Support: