EMD-25452

Single-particle
3.9 Å
EMD-25452
3D View Gallery
Deposition: 19/11/2021
Map released: 12/01/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25452

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7svr summary report (pdf.gz) Map-7svr FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

The complex of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809)

EMD-25452

Single-particle
3.9 Å
EMD-25452
3D View Gallery
Deposition: 19/11/2021
Map released: 12/01/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: The complex of dephosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) and Lumacaftor (VX-809)
Fitted models: 7svr

Deposition Authors: Fiedorczuk K, Chen J
Mechanism of CFTR correction by type I folding correctors.
Fiedorczuk K, Chen J
(2022) Cell , 185 , 158 - 168.e11
PUBMED: 34995514
DOI: doi:10.1016/j.cell.2021.12.009
ISSN: 1097-4172
Grant Support: