EMD-25447

Single-particle
2.7 Å
EMD-25447
3D View Gallery
Deposition: 18/11/2021
Map released: 12/01/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25447

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7svd summary report (pdf.gz) Map-7svd FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Lumacaftor (VX-809)

EMD-25447

Single-particle
2.7 Å
EMD-25447
3D View Gallery
Deposition: 18/11/2021
Map released: 12/01/2022
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Lumacaftor (VX-809)
Fitted models: 7svd

Deposition Authors: Fiedorczuk K, Chen J
Mechanism of CFTR correction by type I folding correctors.
Fiedorczuk K, Chen J
(2022) Cell , 185 , 158 - 168.e11
PUBMED: 34995514
DOI: doi:10.1016/j.cell.2021.12.009
ISSN: 1097-4172
Grant Support: