EMD-25427

Single-particle
3.14 Å
EMD-25427
3D View Gallery
Deposition: 12/11/2021
Map released: 31/05/2023
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25427

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7stf summary report (pdf.gz) Map-7stf FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of KRAS G12V/HLA-A*03:01 in complex with antibody fragment V2

EMD-25427

Single-particle
3.14 Å
EMD-25427
3D View Gallery
Deposition: 12/11/2021
Map released: 31/05/2023
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Ternary complex of antibody-fragment V2 with KRAS G12V/HLA-A*03:01
Fitted models: 7stf

Deposition Authors: Wright KM, Gabelli SB
Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.
Wright KM, DiNapoli SR , Miller MS , Aitana Azurmendi P, Zhao X, Yu Z, Chakrabarti M , Shi W, Douglass J, Hwang MS, Hsiue EH, Mog BJ , Pearlman AH , Paul S , Konig MF , Pardoll DM, Bettegowda C , Papadopoulos N , Kinzler KW, Vogelstein B , Zhou S , Gabelli SB
(2023) Nat Commun , 14 , 5063 - 5063
PUBMED: 37604828
DOI: doi:10.1038/s41467-023-40821-w
ISSN: 2041-1723
Grant Support: