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EMD-25406

Single-particle
3.2 Å
EMD-25406
3D View Gallery
Deposition: 10/11/2021
Map released: 05/04/2023
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25406
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7ssa summary report (pdf.gz) Map and 7ssa FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of pioneer factor Cbf1 bound to the nucleosome

EMD-25406

Single-particle
3.2 Å
EMD-25406
3D View Gallery
Deposition: 10/11/2021
Map released: 05/04/2023
Last modified: 05/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c), synthetic construct, Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Xenopus laevis
Sample: Pioneer factor Cbf1 in complex with the nucleosome
Fitted models: 7ssa

Deposition Authors: Eek P , Tan S
Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions.
Donovan BT, Chen H, Eek P , Meng Z, Jipa C , Tan S, Bai L, Poirier MG
(2023) Mol Cell , 83 , 1251 - 1263.e6
PUBMED: 36996811
DOI: doi:10.1016/j.molcel.2023.03.006
ISSN: 1097-2765
ASTM: MOCEFL