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EMD-25403

Single-particle
3.3 Å
EMD-25403
3D View Gallery
Deposition: 08/11/2021
Map released: 21/09/2022
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25403
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7srs summary report (pdf.gz) Map and 7srs FULL report (pdf.gz)
EMICSS annotations (xml)

5-HT2B receptor bound to LSD in complex with beta-arrestin1 obtained by cryo-electron microscopy (cryoEM)

EMD-25403

Single-particle
3.3 Å
EMD-25403
3D View Gallery
Deposition: 08/11/2021
Map released: 21/09/2022
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: 5-HT2B receptor bound to LSD in complex with beta-arrestin1
Fitted models: 7srs

Deposition Authors: Barros-Alvarez X, Cao C, Panova O, Roth BL, Skiniotis G
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Cao C, Barros-Alvarez X, Zhang S , Kim K, Damgen MA, Panova O, Suomivuori CM , Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, Huttenhain R , Nichols DE, Dror RO , Skiniotis G , Roth BL
(2022) Neuron , 110 , 3154
PUBMED: 36087581
DOI: doi:10.1016/j.neuron.2022.08.006
ISSN: 0896-6273
ASTM: NERNET
Grant Support: