EMD-25401

Single-particle
2.7 Å
EMD-25401
3D View Gallery
Deposition: 08/11/2021
Map released: 21/09/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25401

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7srq summary report (pdf.gz) Map-7srq FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

5-HT2B receptor bound to LSD obtained by cryo-electron microscopy (cryoEM)

EMD-25401

Single-particle
2.7 Å
EMD-25401
3D View Gallery
Deposition: 08/11/2021
Map released: 21/09/2022
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: 5-HT2B receptor bound to LSD
Fitted models: 7srq

Deposition Authors: Barros-Alvarez X, Cao C
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.
Cao C, Barros-Alvarez X, Zhang S , Kim K, Damgen MA, Panova O, Suomivuori CM , Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, Huttenhain R , Nichols DE, Dror RO , Skiniotis G , Roth BL
(2022) Neuron , 110 , 3154
PUBMED: 36087581
DOI: doi:10.1016/j.neuron.2022.08.006
ISSN: 0896-6273
ASTM: NERNET
Grant Support: