EMD-25399

Single-particle
3.3 Å
EMD-25399
3D View Gallery
Deposition: 08/11/2021
Map released: 08/06/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25399

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7sr8 summary report (pdf.gz) Map-7sr8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Molecular mechanism of the the wake-promoting agent TAK-925

EMD-25399

Single-particle
3.3 Å
EMD-25399
3D View Gallery
Deposition: 08/11/2021
Map released: 08/06/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human orexin receptor 2 - G protein complex
Fitted models: 7sr8

Deposition Authors: Yin J, Chapman K
Molecular mechanism of the wake-promoting agent TAK-925.
Yin J, Kang Y, McGrath AP, Chapman K, Sjodt M, Kimura E, Okabe A, Koike T , Miyanohana Y, Shimizu Y, Rallabandi R , Lian P, Bai X , Flinspach M , De Brabander JK , Rosenbaum DM
(2022) Nat Commun , 13 , 2902 - 2902
PUBMED: 35614071
DOI: doi:10.1038/s41467-022-30601-3
ISSN: 2041-1723