EMD-25378

Single-particle
2.41 Å
EMD-25378
3D View Gallery
Deposition: 04/11/2021
Map released: 02/02/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25378

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7sq7 summary report (pdf.gz) Map-7sq7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of mouse PI(3,5)P2-bound TRPML1 channel at 2.41 Angstrom resolution

EMD-25378

Single-particle
2.41 Å
EMD-25378
3D View Gallery
Deposition: 04/11/2021
Map released: 02/02/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Mouse Transient receptor potential-mucolipin 1 apo closed state
Fitted models: 7sq7

Deposition Authors: Gan N , Han Y
Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P 2 and rapamycin.
Gan N , Han Y , Zeng W, Wang Y, Xue J , Jiang Y
(2022) PNAS , 119
PUBMED: 35131932
DOI: doi:10.1073/pnas.2120404119
ISSN: 1091-6490
ASTM: PNASA6