Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-25198

Single-particle
3.7 Å
EMD-25198
3D View Gallery
Deposition: 24/10/2021
Map released: 30/03/2022
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25198
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7slq summary report (pdf.gz) Map and 7slq FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of 7SK core RNP with circular RNA

EMD-25198

Single-particle
3.7 Å
EMD-25198
3D View Gallery
Deposition: 24/10/2021
Map released: 30/03/2022
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: 7SK circular core RNP with MePCE, Larp7 and circular 7SK RNA
Fitted models: 7slq

Deposition Authors: Yang Y , Liu S
Structural basis of RNA conformational switching in the transcriptional regulator 7SK RNP.
Yang Y , Liu S, Egloff S , Eichhorn CD , Hadjian T , Zhen J , Kiss T , Zhou ZH , Feigon J
(2022) Mol Cell , 82 , 1724
PUBMED: 35320752
DOI: doi:10.1016/j.molcel.2022.03.001
ISSN: 1097-2765
ASTM: MOCEFL