EMD-25170

Single-particle
3.82 Å
EMD-25170
3D View Gallery
Deposition: 19/10/2021
Map released: 08/06/2022
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25170

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7sk2 summary report (pdf.gz) Map-7sk2 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Human wildtype GABA reuptake transporter 1 in complex with tiagabine, inward-open conformation

EMD-25170

Single-particle
3.82 Å
EMD-25170
3D View Gallery
Deposition: 19/10/2021
Map released: 08/06/2022
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: GAT-1 in complex with tiagabine
Fitted models: 7sk2

Deposition Authors: Gati C , Motiwala Z
Structural basis of GABA reuptake inhibition.
Motiwala Z , Aduri NG, Shaye H , Han GW , Lam JH , Katritch V , Cherezov V , Gati C
(2022) Nature , 606 , 820 - 826
PUBMED: 35676483
DOI: doi:10.1038/s41586-022-04814-x
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: