EMD-25146
Broadly Neutralizing Antibody 10-40 in complex with prefusion SARS-CoV-2 B.1.351 Spike glycoprotein
EMD-25146
Single-particle3.9 Å
Deposition: 14/10/2021Map released: 04/05/2022
Last modified: 17/01/2024
Sample Organism:
Severe acute respiratory syndrome coronavirus 2
Sample: broadly neutralizing antibody 10-40 in complex with prefusion SARS-CoV-2 B.1.351 spike glycoprotein
Deposition Authors: Casner RG
,
Reddem ER ,
Shapiro L
Sample: broadly neutralizing antibody 10-40 in complex with prefusion SARS-CoV-2 B.1.351 spike glycoprotein
Deposition Authors: Casner RG
,
Reddem ER ,
Shapiro L
An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses.
Liu L ,
Iketani S ,
Guo Y ,
Reddem ER ,
Casner RG ,
Nair MS ,
Yu J,
Chan JF ,
Wang M,
Cerutti G ,
Li Z,
Morano NC ,
Castagna CD ,
Corredor L ,
Chu H ,
Yuan S ,
Poon VK ,
Chan CC ,
Chen Z ,
Luo Y ,
Cunningham M ,
Chavez A,
Yin MT ,
Perlin DS ,
Tsuji M ,
Yuen KY ,
Kwong PD ,
Sheng Z ,
Huang Y ,
Shapiro L ,
Ho DD
(2022) Sci Transl Med , 14 , eabn6859 - eabn6859
,
Iketani S ,
Guo Y ,
Reddem ER ,
Casner RG ,
Nair MS ,
Yu J,
Chan JF ,
Wang M,
Cerutti G ,
Li Z,
Morano NC ,
Castagna CD ,
Corredor L ,
Chu H ,
Yuan S ,
Poon VK ,
Chan CC ,
Chen Z ,
Luo Y ,
Cunningham M ,
Chavez A,
Yin MT ,
Perlin DS ,
Tsuji M ,
Yuen KY ,
Kwong PD ,
Sheng Z ,
Huang Y ,
Shapiro L ,
Ho DD
(2022) Sci Transl Med , 14 , eabn6859 - eabn6859
Grant Support:
- Jack Ma Foundation: (China)