EMD-25145

Single-particle
5.9 Å
EMD-25145
3D View Gallery
Deposition: 14/10/2021
Map released: 19/01/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25145
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7sin summary report (pdf.gz) Map and 7sin FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of negative allosteric modulator-bound inactive human calcium-sensing receptor

EMD-25145

Single-particle
5.9 Å
EMD-25145
3D View Gallery
Deposition: 14/10/2021
Map released: 19/01/2022
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homodimer human calcium sensing receptor
Fitted models: 7sin

Deposition Authors: Park J, Zuo H
Symmetric activation and modulation of the human calcium-sensing receptor.
Park J, Zuo H, Frangaj A, Fu Z , Yen LY, Zhang Z, Mosyak L, Slavkovich VN, Liu J, Ray KM, Cao B, Vallese F, Geng Y, Chen S, Grassucci R, Dandey VP, Tan YZ , Eng E, Lee Y, Kloss B , Liu Z, Hendrickson WA, Potter CS, Carragher B , Graziano J, Conigrave AD, Frank J, Clarke OB , Fan QR
(2021) PNAS , 118
PUBMED: 34916296
DOI: doi:10.1073/pnas.2115849118
ISSN: 1091-6490
ASTM: PNASA6