EMD-25143

Single-particle
2.7 Å
EMD-25143
3D View Gallery
Deposition: 14/10/2021
Map released: 19/01/2022
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25143

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7sil summary report (pdf.gz) Map-7sil FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of positive allosteric modulator-bound active human calcium-sensing receptor

EMD-25143

Single-particle
2.7 Å
EMD-25143
3D View Gallery
Deposition: 14/10/2021
Map released: 19/01/2022
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homodimer human calcium sensing receptor
Fitted models: 7sil

Deposition Authors: Park J, Zuo H
Symmetric activation and modulation of the human calcium-sensing receptor.
Park J, Zuo H, Frangaj A, Fu Z , Yen LY, Zhang Z, Mosyak L, Slavkovich VN, Liu J, Ray KM, Cao B, Vallese F, Geng Y, Chen S, Grassucci R, Dandey VP, Tan YZ , Eng E, Lee Y, Kloss B , Liu Z, Hendrickson WA, Potter CS, Carragher B , Graziano J, Conigrave AD , Frank J, Clarke OB , Fan QR
(2021) PNAS , 118
PUBMED: 34916296
DOI: doi:10.1073/pnas.2115849118
ISSN: 1091-6490
ASTM: PNASA6