EMD-25076

Single-particle
2.9 Å
EMD-25076
3D View Gallery
Deposition: 03/10/2021
Map released: 27/04/2022
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-25076

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7sf7 summary report (pdf.gz) Map-7sf7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

LPHN3 (ADGRL3) 7TM domain bound to tethered agonist in complex with G protein heterotrimer

EMD-25076

Single-particle
2.9 Å
EMD-25076
3D View Gallery
Deposition: 03/10/2021
Map released: 27/04/2022
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Latrophilin 3 (ADGRL3) 7TM domain bound to tethered agonist in complex with mini-G13 protein
Fitted models: 7sf7

Deposition Authors: Barros-Alvarez X , Panova O, Skiniotis G
The tethered peptide activation mechanism of adhesion GPCRs.
Barros-Alvarez X , Nwokonko RM, Vizurraga A, Matzov D, He F , Papasergi-Scott MM , Robertson MJ , Panova O, Yardeni EH , Seven AB, Kwarcinski FE, Su H, Peroto MC, Meyerowitz JG , Shalev-Benami M, Tall GG , Skiniotis G
(2022) Nature , 604 , 757 - 762
PUBMED: 35418682
DOI: doi:10.1038/s41586-022-04575-7
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: