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EMD-24900
CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134
EMD-24900
Single-particle2.6 Å
Deposition: 18/09/2021Map released: 17/11/2021
Last modified: 04/06/2025
Sample Organism:
Homo sapiens,
Mus musculus
Sample: MRGPRX4-Gq MS47134
Fitted models: 7s8p
Deposition Authors: Cao C
,
Fay JF
Sample: MRGPRX4-Gq MS47134
Fitted models: 7s8p
Deposition Authors: Cao C
,
Fay JF
Structure, function and pharmacology of human itch GPCRs.
Cao C ,
Kang HJ ,
Singh I,
Chen H,
Zhang C,
Ye W ,
Hayes BW ,
Liu J ,
Gumpper RH,
Bender BJ,
Slocum ST,
Krumm BE ,
Lansu K,
McCorvy JD ,
Kroeze WK,
English JG,
DiBerto JF,
Olsen RHJ,
Huang XP,
Zhang S ,
Liu Y ,
Kim K,
Karpiak J,
Jan LY ,
Abraham SN,
Jin J ,
Shoichet BK ,
Fay JF ,
Roth BL
(2021) Nature , 600 , 170 - 175
,
Kang HJ ,
Singh I,
Chen H,
Zhang C,
Ye W ,
Hayes BW ,
Liu J ,
Gumpper RH,
Bender BJ,
Slocum ST,
Krumm BE ,
Lansu K,
McCorvy JD ,
Kroeze WK,
English JG,
DiBerto JF,
Olsen RHJ,
Huang XP,
Zhang S ,
Liu Y ,
Kim K,
Karpiak J,
Jan LY ,
Abraham SN,
Jin J ,
Shoichet BK ,
Fay JF ,
Roth BL
(2021) Nature , 600 , 170 - 175
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