EMD-24800
wild-type Escherichia coli stalled ribosome with antibiotic linezolid
EMD-24800
Single-particle2.48 Å
Deposition: 02/09/2021Map released: 17/11/2021
Last modified: 01/07/2026
Sample Organism:
Escherichia coli
Sample: wild-type Escherichia coli stalled ribosome with antibiotic linezolid
Fitted models: 7s1g
Deposition Authors: Young ID
,
Stojkovic V,
Tsai K,
Lee DJ
Sample: wild-type Escherichia coli stalled ribosome with antibiotic linezolid
Fitted models: 7s1g
Deposition Authors: Young ID
,
Stojkovic V,
Tsai K,
Lee DJ
Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics.
Tsai K,
Stojkovic V,
Lee DJ,
Young ID ,
Szal T,
Klepacki D,
Vazquez-Laslop N ,
Mankin AS,
Fraser JS ,
Fujimori DG
(2022) Nat Struct Mol Biol , 29 , 162 - 171
,
Szal T,
Klepacki D,
Vazquez-Laslop N ,
Mankin AS,
Fraser JS ,
Fujimori DG
(2022) Nat Struct Mol Biol , 29 , 162 - 171
Secondary citations:
- Liebschner D, Afonine PV, Baker ML, Bunkoczi G, Chen VB, Croll TI, Hintze B, Hung LW, Jain S, McCoy AJ, Moriarty NW, Oeffner RD, Poon BK, Prisant MG, Read RJ, Richardson JS, Richardson DC, Sammito MD, Sobolev OV, Stockwell DH, Terwilliger TC, Urzhumtsev AG, Videau LL, Williams CJ & Adams PD. (2019) Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix. Acta Crystallogr D Struct Biol, 75, 861 - 877
- & Croll TI. (2018) ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps. Acta Crystallogr D Struct Biol, 74, 519 - 530
- Emsley P, Lohkamp B, Scott WG & Cowtan K. (2010) Features and development of Coot. Acta Crystallogr D Struct Biol, 66, 486 - 501
- Pettersen EF, Goddard TD, Huang CC, Meng EC, Couch GS, Croll TI, Morris JH & Ferrin TE. (2021) UCSF ChimeraX: Structure visualization for researchers, educators, and developers. 30, 70 - 82
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01AI137270
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): F32AI148120
- Other government: S10OD020054
- Other government: S10OD021741
- Other government: U24 GM129541
- Other government: U24 GM129539
- Other government: Simons Foundation (SF349247)
- Other private: W.M. Keck Foundation Medical Research Grant
- Other private: Sangvhi-Agarwal Innovation Award
- Other government: NSF GRFP
- Other private: UCSF Discovery Fellowship