Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-24695
CC6.33 IgG in complex with SARS-CoV-2-6P-Mut7 S protein (non-uniform refinement)
EMD-24695
Single-particle3.3 Å
Deposition: 16/08/2021Map released: 24/08/2022
Last modified: 14/05/2025
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: CC6.33 IgG in complex with SARS-2-CoV-6P-Mut7 S protein
Fitted models: 7ru3
Deposition Authors: Ozorowski G, Turner HL, Ward AB
Sample: CC6.33 IgG in complex with SARS-2-CoV-6P-Mut7 S protein
Fitted models: 7ru3
Deposition Authors: Ozorowski G, Turner HL, Ward AB
Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.
Zhao F 
,
Keating C,
Ozorowski G,
Shaabani N,
Francino-Urdaniz IM,
Barman S,
Limbo O ,
Burns A,
Zhou P ,
Ricciardi MJ,
Woehl J ,
Tran Q,
Turner HL,
Peng L,
Huang D,
Nemazee D,
Andrabi R,
Sok D,
Teijaro JR,
Whitehead TA,
Ward AB,
Burton DR,
Jardine JG
(2022) iScience , 25 , 104914 - 104914
,
Keating C,
Ozorowski G,
Shaabani N,
Francino-Urdaniz IM,
Barman S,
Limbo O ,
Burns A,
Zhou P ,
Ricciardi MJ,
Woehl J ,
Tran Q,
Turner HL,
Peng L,
Huang D,
Nemazee D,
Andrabi R,
Sok D,
Teijaro JR,
Whitehead TA,
Ward AB,
Burton DR,
Jardine JG
(2022) iScience , 25 , 104914 - 104914
Grant Support:
- Bill & Melinda Gates Foundation: OPP1170236 (United States)
- Bill & Melinda Gates Foundation: INV-004923 (United States)