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EMD-24572

Single-particle
3.2 Å
EMD-24572
3D View Gallery
Deposition: 27/07/2021
Map released: 03/11/2021
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24572
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7rmi summary report (pdf.gz) Map and 7rmi FULL report (pdf.gz)
EMICSS annotations (xml)

SP6-11 biased agonist bound to active human neurokinin 1 receptor in complex with miniGs/q70

EMD-24572

Single-particle
3.2 Å
EMD-24572
3D View Gallery
Deposition: 27/07/2021
Map released: 03/11/2021
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Lama glama
Sample: Substance P bound to Neurokinin 1 receptor-miniGs/q70 complex
Fitted models: 7rmi

Deposition Authors: Harris JA, Faust B
Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
Harris JA, Faust B , Gondin AB , Damgen MA , Suomivuori CM , Veldhuis NA, Cheng Y , Dror RO , Thal DM , Manglik A
(2022) Nat Chem Biol , 18 , 109 - 115
PUBMED: 34711980
DOI: doi:10.1038/s41589-021-00890-8
ISSN: 1552-4469