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EMD-24334
cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP
EMD-24334
Single-particle3.24 Å
Deposition: 29/06/2021Map released: 13/04/2022
Last modified: 30/10/2024
Sample Organism:
Homo sapiens,
Mus musculus,
Lama glama
Sample: cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP, trimeric G protein complex and stabilizing antibodies
Fitted models: 7ra3
Deposition Authors: Sun B, Kobilka BK
Sample: cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP, trimeric G protein complex and stabilizing antibodies
Fitted models: 7ra3
Deposition Authors: Sun B, Kobilka BK
Structural determinants of dual incretin receptor agonism by tirzepatide.
Sun B,
Willard FS,
Feng D,
Alsina-Fernandez J,
Chen Q ,
Vieth M,
Ho JD,
Showalter AD,
Stutsman C,
Ding L,
Suter TM,
Dunbar JD,
Carpenter JW,
Mohammed FA ,
Aihara E,
Brown RA ,
Bueno AB ,
Emmerson PJ,
Moyers JS ,
Kobilka TS,
Coghlan MP ,
Kobilka BK ,
Sloop KW
(2022) PNAS , 119 , e2116506119 - e2116506119
,
Vieth M,
Ho JD,
Showalter AD,
Stutsman C,
Ding L,
Suter TM,
Dunbar JD,
Carpenter JW,
Mohammed FA ,
Aihara E,
Brown RA ,
Bueno AB ,
Emmerson PJ,
Moyers JS ,
Kobilka TS,
Coghlan MP ,
Kobilka BK ,
Sloop KW
(2022) PNAS , 119 , e2116506119 - e2116506119