EMD-24320
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C548
EMD-24320
Single-particle3.5 Å
Deposition: 26/06/2021Map released: 04/08/2021
Last modified: 16/10/2024
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: Antibody-antigen complex of SARS-CoV-2 S 6P trimer with C548 Fabs
Fitted models: 7r8o
Deposition Authors: DeLaitsch AT
,
Barnes CO
Sample: Antibody-antigen complex of SARS-CoV-2 S 6P trimer with C548 Fabs
Fitted models: 7r8o
Deposition Authors: DeLaitsch AT
,
Barnes CO
Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.
Muecksch F,
Weisblum Y ,
Barnes CO,
Schmidt F ,
Schaefer-Babajew D ,
Wang Z,
C Lorenzi JC,
Flyak AI,
DeLaitsch AT ,
Huey-Tubman KE,
Hou S,
Schiffer CA,
Gaebler C ,
Da Silva J,
Poston D ,
Finkin S,
Cho A,
Cipolla M ,
Oliveira TY ,
Millard KG,
Ramos V,
Gazumyan A,
Rutkowska M ,
Caskey M,
Nussenzweig MC,
Bjorkman PJ,
Hatziioannou T,
Bieniasz PD
(2021) Immunity , 54 , 1853 - 1868.e7
,
Barnes CO,
Schmidt F ,
Schaefer-Babajew D ,
Wang Z,
C Lorenzi JC,
Flyak AI,
DeLaitsch AT ,
Huey-Tubman KE,
Hou S,
Schiffer CA,
Gaebler C ,
Da Silva J,
Poston D ,
Finkin S,
Cho A,
Cipolla M ,
Oliveira TY ,
Millard KG,
Ramos V,
Gazumyan A,
Rutkowska M ,
Caskey M,
Nussenzweig MC,
Bjorkman PJ,
Hatziioannou T,
Bieniasz PD
(2021) Immunity , 54 , 1853 - 1868.e7
Grant Support: