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EMD-24095

Single-particle
2.27 Å
EMD-24095
3D View Gallery
Deposition: 24/05/2021
Map released: 24/11/2021
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24095
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7n00 summary report (pdf.gz) Map and 7n00 FULL report (pdf.gz)
EMICSS annotations (xml)

Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 673-1025 in complex with AUG-alpha

EMD-24095

Single-particle
2.27 Å
EMD-24095
3D View Gallery
Deposition: 24/05/2021
Map released: 24/11/2021
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: hetero-tetrameric complex of anaplastic lymphoma kinase (ALK) with Augmentor alpha
Fitted models: 7n00

Deposition Authors: Myasnikov AG, Reshetnyak AV , Kalodimos CG
Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Reshetnyak AV , Rossi P, Myasnikov AG, Sowaileh M, Mohanty J, Nourse A , Miller DJ, Lax I, Schlessinger J , Kalodimos CG
(2021) Nature , 600 , 153 - 157
PUBMED: 34819673
DOI: doi:10.1038/s41586-021-04140-8
ISSN: 1476-4687
ASTM: NATUAS