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EMD-24082

Single-particle
2.92 Å
EMD-24082
3D View Gallery
Deposition: 21/05/2021
Map released: 10/11/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24082
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7myo summary report (pdf.gz) Map and 7myo FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of p110alpha in complex with p85alpha inhibited by BYL-719

EMD-24082

Single-particle
2.92 Å
EMD-24082
3D View Gallery
Deposition: 21/05/2021
Map released: 10/11/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Heterodimer of p110alpha with p85alpha
Fitted models: 7myo

Deposition Authors: Liu X, Yang S
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation.
Liu X, Yang S, Hart JR , Xu Y, Zou X, Zhang H, Zhou Q , Xia T, Zhang Y, Yang D , Wang MW , Vogt PK
(2021) PNAS , 118
PUBMED: 34725156
DOI: doi:10.1073/pnas.2109327118
ISSN: 1091-6490
ASTM: PNASA6