EMD-24082

Single-particle
2.92 Å
EMD-24082
3D View Gallery
Deposition: 21/05/2021
Map released: 10/11/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24082

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7myo summary report (pdf.gz) Map-7myo FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of p110alpha in complex with p85alpha inhibited by BYL-719

EMD-24082

Single-particle
2.92 Å
EMD-24082
3D View Gallery
Deposition: 21/05/2021
Map released: 10/11/2021
Last modified: 29/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Heterodimer of p110alpha with p85alpha
Fitted models: 7myo

Deposition Authors: Liu X, Yang S
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation.
Liu X, Yang S, Hart JR , Xu Y, Zou X, Zhang H, Zhou Q , Xia T, Zhang Y, Yang D , Wang MW , Vogt PK
(2021) PNAS , 118
PUBMED: 34725156
DOI: doi:10.1073/pnas.2109327118
ISSN: 1091-6490
ASTM: PNASA6