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EMD-24075
Cryo-EM structure of NTD-directed neutralizing antibody LP5 Fab in complex with SARS-CoV-2 S2P spike
EMD-24075
Single-particle4.46 Å
Deposition: 19/05/2021Map released: 25/05/2022
Last modified: 04/06/2025
Sample Organism:
Homo sapiens,
Severe acute respiratory syndrome coronavirus 2
Sample: Prefusion SARS-CoV-2 spike glycoprotein in complex with LP5 Fab
Fitted models: 7mxp
Deposition Authors: Reddem ER
,
Casner RG
Sample: Prefusion SARS-CoV-2 spike glycoprotein in complex with LP5 Fab
Fitted models: 7mxp
Deposition Authors: Reddem ER
,
Casner RG
Antibody screening at reduced pH enables preferential selection of potently neutralizing antibodies targeting SARS-CoV-2.
Madan B ,
Reddem ER ,
Wang P ,
Casner RG,
Nair MS ,
Huang Y,
Fahad AS,
de Souza MO,
Banach BB,
Lopez Acevedo SN ,
Pan X,
Nimrania R,
Teng IT,
Bahna F,
Zhou T,
Zhang B,
Yin MT ,
Ho DD,
Kwong PD ,
Shapiro L,
DeKosky BJ
(2021) Aiche J , 67 , e17440 - e17440
,
Reddem ER ,
Wang P ,
Casner RG,
Nair MS ,
Huang Y,
Fahad AS,
de Souza MO,
Banach BB,
Lopez Acevedo SN ,
Pan X,
Nimrania R,
Teng IT,
Bahna F,
Zhou T,
Zhang B,
Yin MT ,
Ho DD,
Kwong PD ,
Shapiro L,
DeKosky BJ
(2021) Aiche J , 67 , e17440 - e17440
Grant Support:
- Jack Ma Foundation: (China)