EMD-23951

Single-particle
4.4 Å
EMD-23951
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Deposition: 06/05/2021
Map released: 16/03/2022
Last modified: 29/03/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-23951
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7mqs summary report (pdf.gz) Map and 7mqs FULL report (pdf.gz)
EMICSS annotations (xml)

The insulin receptor ectodomain in complex with three venom hybrid insulin molecules - asymmetric conformation

EMD-23951

Single-particle
4.4 Å
EMD-23951
3D View Gallery
Deposition: 06/05/2021
Map released: 16/03/2022
Last modified: 29/03/2023
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Insulin receptor ectodomain in complex with insulin analog Vh-Ins-HSLQ - asymmetric conformation.
Fitted models: 7mqs

Deposition Authors: Blakely AD , Xiong X , Kim JH, Menting J, Schafer IB , Schubert HL, Agrawal R, Gutmann T , Delaine C, Zhang Y, Artik GO , Merriman A, Eckert D, Lawrence MC , Coskun U , Fisher SJ, Forbes BE , Safavi-Hemami H , Hill CP , Chou DHC
Symmetric and asymmetric receptor conformation continuum induced by a new insulin.
Xiong X , Blakely A , Kim JH, Menting JG, Schafer IB , Schubert HL, Agrawal R, Gutmann T , Delaine C, Zhang YW , Artik GO , Merriman A, Eckert D, Lawrence MC , Coskun U , Fisher SJ, Forbes BE , Safavi-Hemami H , Hill CP , Chou DH
(2022) Nat Chem Biol , 18 , 511 - 519
PUBMED: 35289328
DOI: doi:10.1038/s41589-022-00981-0
ISSN: 1552-4469