EMD-23951

Single-particle
4.4 Å
EMD-23951
3D View Gallery
Deposition: 06/05/2021
Map released: 16/03/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-23951

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7mqs summary report (pdf.gz) Map-7mqs FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The insulin receptor ectodomain in complex with three venom hybrid insulin molecules - asymmetric conformation

EMD-23951

Single-particle
4.4 Å
EMD-23951
3D View Gallery
Deposition: 06/05/2021
Map released: 16/03/2022
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Insulin receptor ectodomain in complex with insulin analog Vh-Ins-HSLQ - asymmetric conformation.
Fitted models: 7mqs

Deposition Authors: Blakely AD, Xiong X
Symmetric and asymmetric receptor conformation continuum induced by a new insulin.
Xiong X , Blakely A , Kim JH, Menting JG, Schafer IB , Schubert HL, Agrawal R, Gutmann T , Delaine C, Zhang YW , Artik GO , Merriman A, Eckert D, Lawrence MC , Coskun U , Fisher SJ, Forbes BE , Safavi-Hemami H , Hill CP , Chou DH
(2022) Nat Chem Biol , 18 , 511 - 519
PUBMED: 35289328
DOI: doi:10.1038/s41589-022-00981-0
ISSN: 1552-4469
Grant Support: